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On-going projects List

Collaborative/Methodological Development Projects

Datasets

Local Collaborator’s

1. RANN ((???))

  • All baseline and 5-year follow-up data have been processed and ready.
    • T1 freesurfer
    • Resting state fMRI
    • Task fMRI (12 tasks)
    • DTI: FA/MD/RD maps and tracular segmentation
  • Work-in-progress
    • Morphometry data (RAVENS maps): will be processed

2. Cognitive Reserve ((???))

  • All baseline and 5-year follow-up data have been processed and ready.
    • T1 freesurfer
    • Resting state fMRI
    • Task fMRI: shape sternberg
    • DTI: FA/MD/RD maps and tracular segmentation
    • WMHI: probability maps have been created.
  • Work-in-progress
    • Morphometry data (RAVENS maps): will be processed

3. Exercise study ((???))

  • All datasets are processed
    • T1 freesurfer
    • Resting state fMRI
    • Task fMRI: Flanker’s and Shape sternberg
    • WMHI
    • DTI

4. Multiple sclerosis

  • T1 freesurfer
  • FLAIR legion load
  • Resting fMRI
  • DTI

5. DIAN study

  • WMHI
  • T1
  • Cognitive

6. Frontotemporal Dimentia ((???), (???))

  • DTI
  • T1 freesurfer

7. Depression RCT (two studies)

  • resting fMRI

8. Maternal perinatal distress

  • some subjects have neonatal MRI (resting fMRI, DTI, T1 VBM)
  • DNA methylation (480K resolution)
  • RNA expression

Public Data

1. ADNI

  • All T1 freesurfer segmentation has been done
  • All PET (amyloid, tau and FDG) have been processed

2. NACC

  • All T1 freesurfer segmentation has been done

Ongoing Projects

1. RCT analysis for neuroimaging - Study 58

  • Zilan Chai
  • WIP
    • Multiple imputation for neuroimagin data
    • Voxel-level analysis R function

2. High-dimensional moderated mediation - RANN/CR + ADNI

  • Seonjoo Lee
  • WIP
    • Simulation study
    • Data Analysis

3. High-dimensional mediation for survival outcomes - ADNI

4. Stratified machine learning -

  • Interpretable in the presence of moderation
  • e.g. dementia transition = mrix anxiety x gender

5. Poisson factor analysis for overdispersed data

  • New student
  • Algorithm development
  • miRNA or RNA data

6. Factor Analysis : Teal’s project (CR)

  • Need to assign a student
  • Conduct factor analysis
  • Test factor structure by young vs old participants

7. Multiple Sclerosis classification

  • Melissa + new student
  • Classify patients with cognitive impairment using Connecitivity maps

References